In 2370, Quark had a particularly dusty bottle of Vulcan port amongst his personal stock, which was regarded as being a considerably expensive and very rare vintage given that it was three centuries old. From this bottle he poured Sakonna a glass, to which she declined. Quark thereafter found the taste disagreeable upon sampling it for himself. (DS9: "The Maquis, Part I")
The existence of Vulcan port would seem most curiously to contradict a previous statement set forth by Spock in "The Conscience of the King", where he noted: "My father's race was spared the dubious benefits of alcohol,". See the article on Alcohol for a more comprehensive discussion of the issue.