The USS Musashi was a Federation starship that was in service with Starfleet in the late 24th century. Mushashi fought in the Dominion War.

In 2375, the Musashi was involved in a series of complicated trades for engineering equipment orchestrated by Ensign Nog of Deep Space 9. Nog traded an induction modulator to the Musashi in exchange for a phaser emitter. (DS9: "Treachery, Faith and the Great River")