The USS Horizon (NCC-176) was a Federation Daedalus-class starship that was in service with Starfleet in the mid-22nd century.
A model of this ship was on display in the school aboard Deep Space 9 in early 2369. (DS9: "The Nagus")
Benjamin Sisko kept a model of this vessel in his office aboard Deep Space 9. (DS9: "Progress" et al.)
In the novel Starfleet: Year One, Captain Alonis Cobaryn was mentioned as taking command of the Horizon in 2167. It was also mentioned in the Strange New Worlds VII short story "Test of Character."