There have been a number of ships named USS Enterprise, and therefore could mean:
- Ocean going vessels
- USS Enterprise (brig), the 19th century brig
- USS Enterprise CV-6, a World War II aircraft carrier
- USS Enterprise CVN-65, a Cold War nuclear aircraft carrier
- Space vessels
- USS Enterprise XCV 330, a pre-Federation Earth starship
- USS Enterprise NCC-1701, a Constitution-class starship
- USS Enterprise (replica), a partial replica of the Constitution-class starship
- USS Enterprise (alternate reality), the Enterprise NCC-1701 as it exists in the alternate reality
- USS Enterprise NCC-1701-A, a Constitution-class refit
- USS Enterprise NCC-1701-B, an Excelsior-class refit
- USS Enterprise NCC-1701-C, an Ambassador-class starship
- USS Enterprise NCC-1701-D, a Galaxy-class starship
- USS Enterprise NCC-1701-E, a Sovereign-class starship
- USS Enterprise NCC-1701-J, a possible future starship
- See also
- Enterprise, for other ships named Enterprise
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