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Memory Alpha

The USS Charleston (NCC-42285) was an Excelsior-class Federation starship in service in the 24th century. In 2364, it was assigned to patrol the Romulan Neutral Zone, and later transported three Human survivors from a cryonic satellite back to Earth. (TNG: "The Neutral Zone")

In early 2368, the Charleston was part of the task force that blockaded the Klingon-Romulan border during the Klingon Civil War. (TNG: "Redemption, Part II")

In the late 2360s, according to a computer display in the Enterprise-D's lounge, Charleston was conducting deep space exploration in Sector 22055. (TNG: Starship Mission Status chart)

The ship's registry and class were not mentioned or seen onscreen, they are derived solely from this piece of background graphics created by the art department.
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