Tuvan Syndrome is a neurological disease affecting such various species, such as Romulans, Vulcans and Rigelians, which typically is degenerative and incurable.
In the normal profile for degeneration, the patient will begin experiencing a loss of motor skills in ten to fifteen years, with life expectancy somewhere in the twenty to twenty-five year range upon contracting it.
In 2375, Section 31 was under the impression that Koval, head of the Romulan Tal Shiar, had contracted Tuvan Syndrome. Or so they led Dr. Julian Bashir to believe, as they convinced him that he was needed to make a positive diagnosis as part of a ruse to expel Senator Kimara Cretak from her chair in the Romulan Senate. (DS9: "Inter Arma Enim Silent Leges")
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