The Tilonus Institute for Mental Disorders is a hospital for psychiatric patients on the planet Tilonus IV.

In 2369 Commander William T. Riker was kidnapped and made to believe he was a patient in ward 47 at the Institute.

Doctor Suna, a psychiatrist there, tried to convince Riker that his being a Starfleet officer was a delusion, just a series of hallucinations that started after he stabbed a man in cold blood.

While there, he also met a woman named Jaya who also claimed to be a kidnapped Starfleet officer, "Commander Bloom of the starship USS Yorktown". He soon realized that she really was a psychiatric patient however, when she tried to use a spoon as a communicator. (TNG: "Frame of Mind")