Thymic sclerosis is a nonfatal disease that affects Denobulans.

In 2152, Doctor Phlox claimed to the Vulcan Doctor Yuris that the pathology of Pa'nar Syndrome was similar to thymic sclerosis, and that a colleague of his on Denobula had asked him to gather information about the condition. Phlox also claimed that thymic sclerosis affected all strata of Denobulan society, and that there had been little success in finding a treatment. (ENT: "Stigma")