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Memory Alpha

Theragen is a gaseous compound. Initially developed as a bio-weapon by the Klingons, at full strength it is a nerve agent that is extremely lethal, but at much smaller doses, it can temporarily deaden certain nerve inputs to the brain, having a calming effect on an insane and/or abnormally enraged person. This non-lethal use was first used on the crew of the USS Enterprise in 2267, following an extended interaction with the effects of interphase space. Leonard McCoy, the ship's Chief Medical Officer, discovered how to use the Theragen derivative to calm the crew long enough for the Enterprise to complete her mission. The medicine is now listed in the Starfleet Medical Database.(TOS: "The Tholian Web")

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