Temporal narcosis
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Temporal narcosis is a condition whereby one experiences overwhelming neurophysical stress when entering another time continuum, in much the same way deep sea divers experience nitrogen narcosis.
In 2369, Captain Jean-Luc Picard experienced temporal narcosis shortly after boarding the USS Enterprise-D, which had become trapped in a temporal fragment. Succumbing to this condition, Picard alternately experienced states of hysteria and panic, before being beamed out of the fragment's influence. (TNG: "Timescape")