The Xindi incident or Xindi crisis was a series of events lasting nearly a year, from March 2153 to February 2154, involving the Enterprise NX-01's attempt to save Earth from destruction by the Xindi. It was a major turning point in the Temporal Cold War, and the incident also helped pave the way for the creation of the Coalition of Planets, a precursor to the Federation.

In March of 2153, acting on false intelligence provided by the Sphere Builders, the Xindi launched a surprise attack on Earth. The Xindi, who had been without a homeworld since the 2030s, had been informed by their protectors that, in the 26th century, Humanity was going to destroy their new homeworld.

Because of this, the Xindi-Primate scientist (and Xindi Council member) Degra had been working for several years on a weapon capable of destroying Earth.