A telepresence unit was a device which utilized telepresence to allow a person to safely control a vessel from a remote location. Telepathy was required to use a telepresence unit, which could transmit brain wave signals through many light years in space.
In 2154, the Romulans utilized a telepresence unit to control two Romulan drone-ships from a command center on Romulus. The crew of Enterprise also created a telepresence unit to prevent the Romulans from continuing their attacks with the prototype drone-ships. Though Commander T'Pol was unsuccessful in operating the unit, the Aenar Jhamel managed to control the device and was able to convince her brother, Gareb (who was controlling the drone-ships,) to stop the attacks. (ENT: "The Aenar")