Seth Goldberg was a Human Starfleet officer in the mid-24th century.

In 2364 he held the rank of captain and was the commanding officer of the USS Callisto. In that year, on stardate 41607.9, he received a mission order about the exploration of Gamma Argus II from Vice Admiral Maxwell Headroom of Starfleet Planetary Geosciences Division. (TNG: "Conspiracy")