Serpent might refer to:

• Aldebaran serpent, a three-headed snake-like creature from the Aldebaran system
• "How Sharper Than a Serpent's Tooth", the second season Animated Series episode
• Kos'karii, a mythological Klingon serpent
• Serpent of Xol, creature from Klingon legends
• Serpent women, otherwise known as female U'tani
• Serpent's Ridge, a location on Bajor
• Serpent worm, an animal eaten by Klingons
• Snake, the reptilian creature

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