Sector 010 was a region of space. A portion of the Romulan Neutral Zone was located in this sector. In 2364, the Federation starships USS Tranquillity Base, USS Non Sequitur, and USS Max Plank were ordered by Starfleet Command to decrease sensor drone surveillance of this sector. (TNG: "Conspiracy")

A year later, NCC-31054 was assigned a deep exploration mission in this sector. (TNG: "The Measure Of A Man")