The Sands Hotel (or the Sands) was a hotel/casino built in 1952, located in Las Vegas, Nevada on Earth. In the holosuite program Bashir 62, a rendition of 1962, the Sands was one of the biggest venues along the Vegas Strip.
Vic Fontaine once recalled to Odo that Frank and Dean dropped in on him once while he was playing at the Sands, back in 1958. Together, the three of them took over one of the blackjack tables and dropped a combined $15,000. (DS9: "His Way")
Following the hostile takeover of his lounge by Frankie Eyes, Vic attempted to get gigs at other local casinos including the D.I., the Sands and the Dunes. None of them returned his calls. (DS9: "It's Only a Paper Moon")
In the Klingon Encounter portion of Star Trek: The Experience, the Sands is briefly visible while flying over the Las Vegas Strip while dodging Korath.