S. Welke was a 22nd century member of United Earth Starfleet, one of the officers listed on the dedication plaque of Enterprise NX-01. Welke was listed in the group of names of representatives from Starfleet Command. (Star Trek: Enterprise set artwork)

In January of 2155, Welke was working in Mission Operations at the Fleet Operations Center on Earth. Welke's office was in room 1067. (ENT: "Demons" set artwork)