Preganglionic fibers connected the ganglion to the central nervous system.
Doctor Julian Bashir mistook a preganglionic fiber for a postganglionic nerve during the oral exam phase of his Starfleet Medical finals. (DS9: "Emissary", "Q-Less", "Distant Voices")
In 2373, The Doctor repaired the damage to the preganglionic fibers in Tom Paris' spinal column after Paris had been attacked by members of the Swarm species. (VOY: "The Swarm")
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