A particle accelerator is a device that propels particles to high speeds. It can be used as a weapon.
In 2371, Quark arranged to have the Maquis gunrunner Sakonna acquire three particle accelerators from the Pygorians. (DS9: "The Maquis, Part II")
The crew of the Silver Blood USS Voyager acquired some particle accelerators in 2375. (VOY: "Course: Oblivion")