Panama City was a coastal city located in the "panhandle" of north-west Florida on Earth.
Trip Tucker was born here and attended Bayshore Elementary School in Panama City, Florida in the early 22nd century, as did one of his former schoolmates, Melissa Lyles. (ENT: "Fusion")
Following the Xindi attack on Earth, Tucker's parents moved from the old home in Panama City to a new house in Mississippi. (ENT: "The Augments")