Murphy may refer to:
- In-universe
- Murphy (Enterprise), an officer on the Enterprise-D
- Murphy (science), a science division officer on board Voyager
- Murphy (security), a security officer on board Voyager
- Performers
- Donna Murphy, actress who played Anij in Star Trek: Insurrection
- Murphy (actor), a child actor in TNG: "New Ground"
- Production staff
- Murphy (lamp operator), worked on TNG: "Suddenly Human"
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