In 2373, the Maquis who had survived the assault on them by the Dominion, including Rebecca Sullivan, faked a supposed missile launch against Cardassia to let Michael Eddington know they were safe on Athos IV. Benjamin Sisko and Martok took this very seriously, as they knew the Dominion would start a war if the weapons hit Cardassian targets. There were also fears they were using the cloaking devices the Klingons had given to the Maquis. Sisko enlisted Eddington's help in disarming the supposed missiles and the former Maquis leader accompanied him to Athos IV, where Sisko discovered the truth. (DS9: "Blaze of Glory")
In 2387, the Romulan mining vessel Narada was armed with advanced missiles that separated into numerous smaller projectiles when approaching a target. These weapons were used to deadly effect during the Narada's incursion into the alternate reality, most notably during the Battle of Vulcan.