Leo (constellation)
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Leo was a constellation from the point of view of Earth, named after its shape of a lion.
The constellation Leo includes the stars Regulus (Alpha Leonis), Denebola (Beta Leonis; possibly Deneb) and Wolf 359, the site of Starfleet's disastrous battle against the Borg in 2367.
The similarity between the sounding of Denebola and Denobula should be noted.
In 2063, Lily Sloane pointed to an incoming Borg energy weapon and asked Zefram Cochrane what it was, but he thought she was pointing to "the constellation Leo." (Star Trek: First Contact)
Star Trek creator Gene Roddenberry was born in the zodiac sign Leo.