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Karen Westerfield (born 26 May 1956; age 67) is a makeup artist who worked as Beauty and Prosthetics makeup artist on Star Trek: The Next Generation (1991-1992), Star Trek: Deep Space Nine (1992-1999), Star Trek: Voyager (1994-1996 and 2000), and Star Trek: Enterprise as well as the Star Trek films Star Trek VI: The Undiscovered Country and Star Trek Nemesis. She is most well known as being the person who applied Armin Shimerman's makeup for his character Quark throughout the seven-year run of Deep Space Nine. Her first Star Trek contribution was as day player makeup artist for a Klingon character in the sixth season of The Next Generation. She previously worked as a crafts person with Michael Westmore on the 1987 fantasy film Masters of the Universe which co-starred Frank Langella, Anthony De Longis, Christina Pickles, Chelsea Field, and Robert Duncan McNeill. At the Destination Star Trek convention in Birmingham, UK on 20 October 2018, Westerfield "re-united" with Shimerman when she provided his prosthetic makeup for the first time following the end of Deep Space Nine for a photo ops with the fans. ("Behind the Masks" panel at Destination Star Trek Birmingham, 21 October 2018)

Her work on Star Trek earned her the following Emmy Award nominations and wins:

In 1997 Westerfield received an Emmy Award nomination in the category Outstanding Makeup for a Miniseries or a Special for her work on Alien Nation: The Enemy Within, shared with Rick Stratton, Richard Snell, Craig Reardon, Janna Phillips, David Abbott, Edouard F. Henriques, and Kenny Myers and in 2005 she received another Emmy Award nomination in the category Outstanding Makeup for a Miniseries, Movie or a Special (Non-Prosthetic) for her work on Lackawanna Blue.

Beside her work on Star Trek, Westerfield also worked as makeup artist on the television comedy Carol Leifer: Gaudy, Bawdy & Blue (1992, with Gloria Ponce), Alien Nation: The Udara Legacy (1997, with David Abbott, Zoltan Elek, Carolyn Ferguson, Edouard F. Henriques, Janna Phillips, Rick Stratton, Craig Reardon, and Ellen Powell), How the Grinch Stole Christmas (2000), Town & Country (2001, with Janice Alexander, Chris McBee, Carol A. O'Connell, Heather Koontz, Barbara Ronci, and Toni-Ann Walker), Spider-Man (2002), The Polar Express (2004), Mr. & Mrs. Smith (2005), The Dead Girl (2006, with Ed French, Richard Redlefsen, and Rick Stratton), Pirates of the Caribbean: At World's End (2007), and Beowulf (2007).

More recently, she worked as makeup artist on the television specials 13th Annual Prism Awards (2009) and 14th Annual PRISM Awards (2010) and on the television comedy Listen to Grandpa, Andy Ling (2012).

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