Hypochondria is a psychological condition where a person experiences abnormal and chronic anxiety over imagined illnesses.

Reginald Barclay suffered from hypochondria, as did William Telfer. It could be treated with medicine or counseling. (TNG: "Realm of Fear", "Genesis"; VOY: "Good Shepherd")

In 1996, when Tuvok refused to removed his shirt and experience 20th century weather, Tom Paris commented, "Vulcans. Deep down you're all a bunch of hypochondriacs." (VOY: "Future's End")

In Photons Be Free, the holonovel written by the USS Voyager's EMH, the character based on Harry Kim, Kymble, was a hypochondriac. (VOY: "Author, Author")