A housekeeper is a person who cared for the house and the belongings of the owner.
M-4 served as butler, housekeeper, gardener, and guardian for Flint. (TOS: "Requiem for Methuselah")
Aamin Marritza provided handsomely for his housekeeper prior to his departure from Kora II in 2369. (DS9: "Duet")
In an anti-time future, Jessel served as housekeeper for Data. (TNG: "All Good Things...")
Mila served as housekeeper for Enabran Tain for over thirty years until her death in 2375. (DS9: "Improbable Cause", "The Dogs of War", "What You Leave Behind")