Guidance and Navigation (or simply Guidance) was a department, division, or position within Starfleet's Fleet Operations Center on Earth. (ENT: "Demons" set artwork)
In January of 2155, Starfleet officers T. Chavez, A. Codron, A. Dominguez, A. Fukai, A. Geary, M. Hoffman, L. Ortiz, and F. Zimmerman worked in (or as) Guidance and Navigation.
Guidance and Navigation (listed as Guidance & Nav or Guidance) was seen on directory listings seen on the set of "Demons".
, like many of the other divisions, departments, or positions on the listing, is a reference to NASA
terminology, in this case, the "Guidance Officer".