Guidance and Navigation (or simply Guidance) was a department, division, or position within Starfleet's Fleet Operations Center on Earth. (ENT: "Demons" set artwork)

In January of 2155, Starfleet officers T. Chavez, A. Codron, A. Dominguez, A. Fukai, A. Geary, M. Hoffman, L. Ortiz, and F. Zimmerman worked in (or as) Guidance and Navigation.