The gossamer mouse is a type of sensitive lab animal kept in sickbay on board the USS Enterprise. This species of mammal, as well as its organs, are naturally translucent in appearance.

In 2269, James T. Kirk called sickbay to see if the mysterious X-waves the ship was just probed with had any effect on the sensitive lab animals. Dr. McCoy reported that the gossamer mice showed no sign of shock.

Once the crew and all organic material aboard ship began to shrink, it was observed by Christine Chapel that the gossamer mice had all escaped from their cages. (TAS: "The Terratin Incident")