Genesis could refer to:

• Genesis (planet), the planet created by the Genesis Device
• Genesis cave, phase II of the Genesis Project
• Genesis Device, the product responsible for creating the Genesis Planet
• Project Genesis, the project responsible for the creation of the Genesis Device
• Symbiogenesis
• "Genesis", the seventh season episode of Star Trek: The Next Generation
• Genesis Force, a novel by John Vornholt
• CCG: Genesis, a Star Trek Customizable Card Game expansion

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