First Contact could refer to:

• First contact, the term concerning situations and procedures when meeting a new species
• First contacts, a list of first contacts between civilizations
• First Contact, a science fiction story published by Incredible Tales in 1953
• First Contact, a drawing by fourth grader Haley about first contact
• First Contact Day, a holiday celebrated in the Federation
• "First Contact", the fifteenth episode of season four of The Next Generation
• Star Trek: First Contact, the eighth feature film
• CCG: First Contact, an expansion of the Customizable Card Game
• CCG: Enhanced First Contact, an expansion of the Customizable Card Game

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