The Durala system was a Federation Alliance held star system during the Dominion War.

In mid-2374 General Martok reported to Captain Benjamin Sisko that three Klingon cruisers were bolstering up the defense of the Durala system. Sisko was pleased by the news, stating that he just hopes they can hold out until Starfleet can send reinforcements. He was then assured that the Klingons would hold out and that Martok would see to it. (DS9: "The Reckoning")