A drone could refer to the following:
- Borg drone, a member of the Borg collective.
- Class-5 intelligence drone, a type of Federation sensor drone used for intelligence-gathering purposes.
- Drone (Shore Leave Planet), worker robots on the Shore Leave planet.
- Federation cargo drone, automated Federation freighters in the 24th century.
- NCC-G1465, Federation cargo drone vessels in the 23rd century.
- Romulan drone-ship, an advanced experimental attack ship in the 22nd century.
- Sensor drone, an automated probe used for espionage and reconnaissance.
- Son'a drone, a small flying device used by the Son'a.
- Target drone, a small unmanned device.