Drexler could refer to:
- People
- D. Drexler, a 22nd century member of Earth Starfleet.
- Doug Drexler (Starfleet), a Starfleet officer in the 2360s and 70s.
- Places
- Drexler outpost, an outpost located in the Omega sector.
- Drexler sector
- Production staff
- Doug Drexler, a production artist.
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