The Selcundi Drema sector, also called the Drema Quadrant, contained five planetary systems. This sector was first explored by the USS Enterprise-D on stardate 42695.3. The main reason for exploration was because unmanned probes discovered unusual levels of geological activity in all five planetary systems.

The first system was charted after 42695.3. The last unmanned probe showed that one of the planets in this system had a thriving ecosystem. By the time the Enterprise had scanned the planet, it had been destroyed by geological instability.

The Enterprise entered the second system on stardate 42696.3. This would be the first system that Acting Ensign Wesley Crusher would perform a planetary geological survey of the planets in the sector.

By stardate 42737.3, the Enterprise had been in the sector for six weeks. The starship had completed surveys of the second and third systems.

The next system, the Selcundi Drema system, contained the planets Drema IV, the homeworld of the Dremans, and Drema V. (TNG: "Pen Pals")