Dilithium ore is a valuable ore from which dilithium is extracted.

Cargoes of dilithium ore were commonly transported by Earth Cargo Service freighters in the 22nd century. (ENT: "Fortunate Son")

The Cardassian station Terok Nor used Bajoran slave labor to mine this ore during the Occupation. In the ore processing area of the station, temperatures could be as high as 55 °C. (DS9: "Civil Defense")