Cloud creature could refer to:
- The dikironium cloud creature, a strange creature on Argus X
- Calamarain, the lifeform from TNG: "Deja Q"
- Class J nebula lifeform, the lifeform discovered by USS Voyager in the Delta Quadrant
- Companion, the creature that lived with Zefram Cochrane in the Gamma Canaris region
- The cosmic cloud, the creature from TAS: "One of Our Planets Is Missing"
- Nucleogenic cloud being, the nebula-sized lifeform in the Delta Quadrant