In 2268, the crew of the USS Enterprise answered a distress call from a colony. There were a hundred men, women, and children in this colony. According to the distress call, they were under attack by an unidentified starship. When a Klingon battle cruiser was detected approaching this planet, CaptainJames Kirk assumed that the Klingons were responsible for the attack. The Klingons would steadfastly deny any involvement in the destruction of the colony.
According to Star Trek: Star Charts, in 2378, Beta XII-A was quarantined. The planet was located in the Beta Leonis Minoris planetary system. (pg. 62) Beta Leonis Minoris was a binary star system. Beta Leonis Minoris A was a G-class star with a magnitude of +3, which was ten times brighter than Sol. Beta Leonis B was a G-class star. In 2378, the Beta Leonis Minoris system was located in or near Federation space. (pg. 62)