Events
- The Federation has become an even more powerful entity, with species such as Klingons, Ithenites and Xindi among its citizenry. (ENT: "Azati Prime")
- Some fans interpret this to mean that the Klingon Empire itself will join the Federation, although this isn't necessarily true. Daniels' statement indicates that the Federation includes Klingons, which may also refer to officers such as Worf.
- A Federation time-travel pod travels to the 22nd century. (TNG: "A Matter of Time")
- Had the Kelvan invasion force into the Milky Way Galaxy remained in control of the USS Enterprise, it was theorized that the starship would arrive in the Andromeda Galaxy sometime during this century. However, the Starfleet crew regained control of the vessel, forged a cooperation with the Kelvans, and launched a robot ship towards Andromeda proposing an alliance between the Federation and the Kelvan Empire. (TOS: "By Any Other Name")
- 2550s - The Battle of Procyon V. The forces of the Federation defeat the invasion of the Sphere Builders and force them back into their own trans-dimensional realm. The starship USS Enterprise-J is instrumental in this battle. (ENT: "Azati Prime")
- 2562 - A neutron star in a binary star system in the Kavis Alpha sector explodes. (TNG: "Evolution")
- 2573 - A component that will be used in the Xindi destroyer/probe is manufactured. It is sent to the Xindi in the 22nd century by the Sphere Builders. (ENT: "The Expanse")
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