- Montgomery Scott joins Starfleet and begins his engineering career. Over the next 52 years, he serves on a combined total of eleven freighters, cruisers and starships. (TNG: "Relics")
- Another starship disappears near Taurus II. (TAS: "The Lorelei Signal")
- Chekov's age from Star Trek alters his age from TOS: "Who Mourns for Adonais?", which has him born in 2245.