- The Warp Five Complex is officially opened by Zefram Cochrane as part of the NX Program. (ENT: "Broken Bow")
- The Earth survey ship SS Tomobiki is launched. (TNG: "Up The Long Ladder")
- This is the last year Cochrane is accounted for, suggesting his dissapearance from Alpha Centauri colony was during or after this year.
- In "The Lorelei Signal", Kirk states in his log that ships have been disappearing in the region "during the last a 150 years", suggesting the first ship disappeared around 2119. However, the year does not seem to fit in with the statement of a disappearance in "precisely every 27.346 star-years". The dates which the disappearances would have occurred would be: 2105, 2132, 2159, 2187, 2214, 2241 and finally in 2269, assuming a star-year is the same as a year.